Calming Supplements for Anxious Dogs: Canine Chill Pills!

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Dog Health By Meg Marrs 20 min read July 19, 2021

Calming Supplements for Dogs

Pacing, excessive grooming, tummy troubles — the symptoms of canine anxiety can leave your pooch on edge.

Not only is anxiety emotionally bothersome for your dog, but it can have physical side effects too, making managing it a must. 

Recognizing anxiety in your dog is fairly easy, but treating it is another bag of bones entirely, thanks to the sheer number of treatment options out there. Calming supplements are one potential option, and they continue to grow in popularity with some pup parents. 

We’ve fetched the facts about calming supplements to give you a clearer picture of what might work for you and your doggo.

Read on to learn more or just check out our quick picks if you’re in a hurry!

Calming Supplements for Anxious Dogs: Quick Picks

  • #1 Gracie To The Rescue’s Calming Treats [Best Socially Responsible Treats — ALSO Best Organic Option] These chews feature organic ingredients like hemp seed oil and chamomile while also donating supplements to local animal shelters for every chew container sold.
  • #2 Finn Calming Chews [Best Soft Calming Treats] These beef liver-flavored calming treats contain several different organic ingredients designed to soothe your canine’s frazzled nerves from hemp and l-typtophan to chamomile and melatonin.
  • #3 FurroLandia Hemp Calming Treats [Best Hemp-Based Calming Treats]These hemp-based treats are made with a variety of ingredients designed to help your dog relax, including chamomile, valerian root, and more.
  • #3 VetriScience Composure Chews [Best Calming Treats for Picky Pooches]Calming treats can’t work if your dog won’t eat them, but these supplements come in four different flavors (including a flavorless liquid) to tempt your pup’s picky palate.

How Do Calming Supplements Work?

Calming supplements contain ingredients that promote relaxation, which may take the edge off mild to moderate cases of canine anxiety.

The efficacy of these supplements varies. Some studies link the active ingredients to an improvement in overall anxiety while others dismiss their claims entirely. 

This makes talking to your vet a must before trying any canine calming supplement to ensure the right fit. 

Ingredients vary by supplement, but the most common are: 

  • Valerian root: Often used by people as a sedative, valerian root may help calm anxious dogs. In fact, dogs who were allowed to smell valerian root extracts exhibited decreased vocalizations and activity in a kennel  environment (where anxiety runs rampant ) according to a study published in Applied Animal Behavior Science. Valerian root isn’t for all dogs, however, and can have adverse effects in some, especially those on medication.
  • L-theanine: The amino acid L-theanine is believed to increase dopamine in the brain, easing anxiousness. A study published in a 2015 issue of Journal of Veterinary Behavior found that L-theanine reduced symptoms in dogs prone to storm-associated anxiety. Perhaps most encouraging, owner satisfaction with the treatment in the study was 94%.   
  • L-tryptophan: Believed to increase serotonin levels in the brain, L-tryptophan may help your dog regulate his anxiety. It’s shown promise in one study published in a 2000 issue of Journal of the American Veterinary Medical Association, as it appeared to reduce aggression and hyperactivity, common side effects of anxiety. However, this study had a pretty limited scope (it only involved 33 dogs), so more research is needed.
  • Chamomile: Found to have a mild sedative effect, chamomile may also have anti-anxiety properties. Unfortunately, while it is thought to be safe for dogs, and one of its primary active ingredients (apigenin) is relatively well-understood, controlled studies with canines have yet to take place. 
  • CBD: CBD or cannabidiol is a plant extract that’s often used to treat anxiety in humans. While there are only a handful of dog studies to-date and more research is necessary, there is some encouraging data available. One 2018 study published in a 2018 issue of Journal of the American Holistic Veterinary Medical Association concluded that CBD is typically well-tolerated by dogs, and a 2019 survey of veterinarians found that many reported it to be effective at treating anxiety (as well as pain and seizures). CBD typically appears as CBD oil or hemp in dog supplements.
  • Melatonin: A hormone that promotes relaxation and sleep, melatonin is often included in calming treats to help anxious dogs suffering from hyperactivity. There are no clear cut scientific studies surrounding dogs and melatonin, though some vets find it effective in alleviating stress caused by separation anxiety, fireworks, and storms.

A few ingredients that are used less often and are less studied, include:

  • Passion flower: Passion flower is a plant believed to have calming or sedative effects on dogs in homeopathic medicine. There are no definitive scientific studies to back-up this claim, nor verify its safety for dogs.
  • Ginger: We can’t find any studies specifically investigating the safety or efficacy of ginger in dogs, but it is well-known for calming properties on the human stomach. Nevertheless, one 2017 study published in Indian Journal of Pharmaceutical Education and Research has also linked it to reducing overall anxiety in lab mice. 
  • Thiamine: Also known as Vitamin B1, thiamine is linked to reducing anxiety in humans. However, no study thus far has examined its use, efficacy, or safety in canines.  
  • Helianthemum nummularium: Results are mixed on the overall effectiveness of this plant (which is also known as rock rose) against anxiety, according to a 2010 study published in Annals of Epidemiology. Extracts of the rock rose are typically prepared in homeopathic remedies, which are typically not shown effective in empirical trials. As put by the study’s authors: “it is likely that the placebo effect operates to a significant extent in both approaches.” 
  • Clematis vitalba: Commonly known as old man’s beard, this flower is used to treat anxiety in homeopathic circles, but no studies have been done on humans or canines to verify this claim or the safety of the extract.  
  • Impatiens glandulifera: Also referred to as Himalayan balsam, this plant has long been used in folk medicine to treat ailments including anxiety. In limited studies, however, the extract hasn’t shown a change in lab mice behavior, and there have been no controlled studies conducted on dogs
  • Prunus cerasifera: Also called cherry plum, this plant and other Bach Flower Remedies are popular among some owners, but they have not been shown to have significant impact on human anxiety (or any other ailment) in studies. 
  • Ornithogalum umbellatum: Known by its common name Star of Bethlehem, this supplement demonstrates the fact that caution is important when using natural supplements, and many are not safe. In fact, this additive is potentially dangerous and may cause irreversible blindness when administered to dogs, according to one study. 
  • Colostrum calming complex: Also called C3 by its manufacturer, VetriScience, colostrum calming complex is made using cow’s milk obtained within 12 hours of the birth of a calf. The company states that the nutrient-dense complex contains amino acids including decapeptide that boost the effect of gamma-Aminobutyric acid, a neurotransmitter that can make the brain less reactive to stressful stimuli. Amino-rich formulas derived from colostrum have shown promise in a 2005 study of human Alzheimer patients published in Regulatory Peptides. However, no studies specifically using C3 have been done on humans or dogs.
  • Zylkene: Zylkene (beef-hydrolyzed milk protein, aka alpha-S1 tryptic casein/alpha-casozepine) is quite similar to the colostrum calming complex and works in essentially the same way.
talk to your vet

Always check with your vet before giving your dog a calming supplement.

Some dogs may be more sensitive to certain ingredients than others, and medications can affect the way some supplements affect your pet’s health.

Your pupper may also be experiencing anxiety due to a medical condition, so it’s important to rule any out before treatment.

The Best Calming Supplements for Dogs 

As we mentioned above, the market is full of calming supplements for dogs that contain a host of ingredients, both natural and man-made. Below, we’ve sorted out the best calming supplements to help your pooch chill out and live his best doggone life.

1. Gracie To The Rescue Calming Treats

About: Gracie To The Rescue’s Calming Treats are made with organic ingredients, including hemp seed oil and chamomile powder. The formula is intended for pups aged 12 weeks and above.

Most Socially Responsible Calming Supplements

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Gracie To The Rescue Calming Treats for Dogs | 120 Soft Chews Dogs -Treats for Anxiety Relief, Separation, Motion Sickness, Hyperactive Behavior, Composure Aid, Thunder Storms, Chewing & Barking

Gracie To The Rescue Calming Treats

Designed to help your canine chill without completely conking out, these treats feature a variety of anxiety-lowering ingredients.


  • Each container contains 120 treats
  • Have calming properties without causing drowsiness, per the manufacturer 
  • Company has a “Paw It Forward” campaign, where a week’s supply of supplements are donated to a shelter for every container of treats sold
  • Made in the USA

Options: Only available in one size, concentration, and flavor.

Ingredients List

Organic Hemp Seed Oil, Organic Hemp Protein Powder, Organic Chamomile Powder, Organic Passion Flower, Valerian Root...,

L-Tryptophan, Organic Ginger Root Powder, Oat Flour, Palm Fruit Oil, Rice Bran, Rice Flour, Flaxseed Meal, Natural Duck Flavoring, Sunflower Lecithin, Coconut Glycerin, Powdered Cellulose, Sorbic Acid, Rosemary Extract, Mixed Tocopherols


The organic ingredients get a tail wag from us, along with the use of ingredients found to be pup-friendly, like hemp-based products, chamomile, valerian root, and more. The lack of drowsiness is a plus with owners.


Some owners found the chews to be a bit crumbly, which may be annoying if you plan on taking these treats on-the-go.

gracie rescue treats
Hands-On Experiences

I had the chance to try Grace to the Rescue Calming Treats with my pooch Remy. She was a big fan and found that it worked well for her four footer.

While I can see where some users found these chews to be on the crumbly side, I didn’t find this to be an issue. They held up just fine and were easy to dispense to Rem.

calming chews

Remy was happy to nom these chews right down. We also love that this organization gives back to local animal shelters. Plus Gracie, the company mascot, is a decent Remy lookalike, which is a nice bonus.

Note: I’ve met the founder of Gracie to the Rescue in person while spending time in Austin, and while we haven’t let this fact affect our review, it’s something I want to disclose.

2. Finn Calming Chews

About: Finn’s Calming Chews are liver-flavored soft chews that calm your dog’s nerves through the use of organic hemp powder as well as other calming ingredients like chamomile, passion flower, and L-Tryptophan.

Great Soft Calming Chews

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Finn Calming Chews

Soft beef liver-flavored chews that include calming ingredients like L-Tryptophan and passion flower.


  • Beef liver flavored soft chews that dogs enjoy, with 90 chews per tin
  • Includes several calming ingredients including organic hemp powder, passion flower, l-tryptophan, chamomile, and melatonin
  • Made with no cellulose powder, silicon dioxide, maltodextrin, corn, soy, or wheat
  • Each batch of chews is lab-tested and tracked through the supply chain from ingredient supplier, manufacturing, and processing to ensure safety

Options: Only available in one size, concentration, and flavor.

Ingredients List

Organic Hemp Powder, Organic Passion Flower, L-Tryptophan, Valerian Root, Organic Ginger Root, L-Theanine...,

Organic Chamomile, Melatonin


These chews contain passion flower, L-Trytophan, ginger root, chamomile, and melatonin, which are all ingredients that potentially may reduce anxiety and stress. The additional lab testing also puts many owners at ease.


Fairly expensive, with only 90 chews per tin. Considering a 60lb dog would need three of these chews a day, it’s easy to see how a large dog could go through these chews fairly quickly!

3. PremiumCare Calming Treats

About: PremiumCare Calming Treats are the perfect size for owners in search of on-the-go anxiety management. The 120-count jar makes ongoing or as-needed administration easy, and it is made with organic hemp-based ingredients.

Best Owner-Rated Calming Treats

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PREMIUM CARE Calming Treats for Dogs - Made in USA - Helps with Dog Anxiety, Separation, Barking, Stress Relief, Thunderstorms and More - Natural Calming Relaxer for Aggressive Behavior - 120 Chews

PremiumCare Calming Treats for Dogs

These extremely well-rated soft chews are duck-flavored and feature several relaxation-promoting ingredients.


  • Duck flavored soft chews are tasty and easy to eat
  • Made in the USA with no corn, soy, or dairy
  • Suitable for all dog breeds and ages
  • Work by calming your dog rather than sedating, according to the manufacturer

Options: Only available in one size, concentration, and flavor.

Ingredients List

Organic Hemp Seed Oil, Organic Hemp Protein Powder, Organic Chamomile Powder, Organic Passion Flower, Valerian Root...,

L-Tryptophan, Organic Ginger Root Powder, Oat Flour, Palm Fruit Oil, Rice Bran, Rice Flour, Flaxseed Meal, Natural Duck Flavoring, Sunflower Lecithin, Coconut Glycerin, Powdered Cellulose, Sorbic Acid, Rosemary Extract, Mixed tocopherols


These supplements contain chamomile powder, L-Trytophan, and ginger root powder, which are all potentially good for treating anxiety and thought to be safe. Effectiveness won heaps of praise from owners, while the duck flavor didn’t get any complaints from pooches. Perfectly snack-sized, they fit easily into treat pouches or daily medication trays.


Some inactive ingredients can be an issue with pups with food sensitivities. Additionally, it is important for owners to realize that despite containing hemp seed oil and hemp powder, these treats do not contain significant amounts of CBD. 

4. Furrolandia Hemp Calming Treats

About: Furrolandia Hemp Calming Treats are bite-sized treats made with 100 percent natural ingredients. Grain-free and easy to chew, the treats include hemp and other ingredients that may help soothe your pooch. 

Best Hemp-Based Calming Treats

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Hemp Calming Treats for Dogs - Helps Keep Your Dog Calm And Relaxed - Separation - Storms - Fireworks - Aggressive Behavior - Natural Calming Aid - Hemp Oil for Dogs - 170 Soft Chews - Made in USA

Furrolandia Hemp Calming Treats

Made with hemp derivatives and several different calming ingredients, these bacon-flavored chews are made in the USA without any added sugar.


  • Suitable for all dog breeds, with dosages listed from toy to giant
  • The 170-count container lasts 30-170 days, depending on your dog’s size
  • Made in the USA with no corn, soy, or sugar
  • Come in an enticing bacon flavor

Options: Only available in one size, concentration, and flavor.

Ingredients List

Hemp Seed Meal, Hemp, Cold Pressed Virgin Hemp Oil, Valerian Extract, Chamomile Extract...,

Passion Flower, L-tryptophan, Organic Minerals, Magnesium


Taste is a high point, with most doggos happily accepting the treat with no fuss. Owners report results within 20-40 minutes of taking the treats, making them ideal for storm-fearing pups if you have advanced notice. 


High anxiety dogs may need something more powerful. Sizing can be less than uniform, though this may be a manufacturing issue. Theoretically, cold-pressed hemp oil may contain CBD, but the manufacturer doesn’t indicate as much on the product packaging, so it is unclear whether this supplement contains any or not. 

5. VetriScience Composure Chews

About: VetriScience Composure Chews are calming treats that can be given daily or on an as-needed basis for storms and other anxiety triggers. Made to calm rather than sedate, the manufacturer reports that these won’t leave your pup drowsy.

Best Calming Treats for Picky Pooches

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VetriScience Laboratories Composure, Calming Support for Dogs, Naturally Sourced Chews to Provide Anxiety Relief for Anxious & Nervous Dogs. 60 Bite Sized Chews

VetriScience Composure Chews

Available in four different flavors, these quick-acting chews are ideal for finicky four-footers who refuse other supplements.


  • Suitable for dogs of all sizes and ages
  • Veterinarian-approved formula 
  • Made in the USA 
  • Starts working within 30 minutes
  • Soft chew is suitable for most dogs and can be crumbled over food

Options: Offered in one concentration, four flavors, and two quantities: 60 and 120-count packages.

Ingredients List

Thiamine, Colostrum Calming Complex, L-Theanine, Brewer's Yeast, Canola Oil...,

Chicken Liver Flavor, Citric Acid, Glycerin, Mixed Tocopherols, Propionic Acid, Maltodextrin, Sodium Alginate and Calcium Sulfate, Rosemary Extract, Silicon Dioxide, Soy Lecithin, Vegetable oil


We love that this supplement is veterinarian-approved, and it contains multiple ingredients with potential anxiety-relieving effects. The product’s taste gets a tail-wag of approval from pooches, while many owners enjoyed that the formula doesn’t leave puppers groggy but lasts up to four hours.


Some ingredients (chicken liver flavor) can be an issue with dogs with food sensitivities. And while many owners were pleased with the product, it may not be strong enough for moderate to high anxiety.

6. NaturVet Quiet Moments Calming Aid

About: The NaturVet Quiet Moments Calming Aid is a soft chew suitable for dogs of all sizes. Combining calming chamomile with the sedative properties of melatonin, it may help your pooch remain calm during those pesky fireworks and thunderstorms.

Great Quick-Acting Calming Treats

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NaturVet Quiet Moments Calming Aid Dog Supplement, Helps Promote Relaxation, Reduce Stress, Storm Anxiety, Motion Sickness for Dogs (Quiet Moments, 180 Soft Chews)

NaturVet Quiet Moments Calming Aid

Designed to work in as little as 30 minutes, these calming aids are a good choice for addressing mild to moderate anxiety.


  • Suitable for mild to moderate canine anxiety according to the manufacturer
  • Added ginger helps soothe sour tummies
  • Reportedly provides comfort and relief within 30 minutes
  • Safe for dogs over 12 weeks old

Options: Available in one flavor, one concentration, and two quantities: 70 and 180-count tubs.

Ingredients List

Chamomile, Passion Flower, Thiamine, Ginger, L-Tryptophan...,

Melatonin, Brewer’s Dried Yeast, Fish Oil, Flaxseed Meal, Glycerin, Lecithin, Natural Flavoring, Oat Groats, Rice Flour, Sorbic Acid, Vegetable Oil, and Wheat Germ.


Dogs approve of the flavor, and owners love their eagerness to eat up. It contains a variety of potentially useful supplements for treating anxiety, and the included melatonin is great for helping restless pups settle at bedtime. 


Dogs with extreme anxiety will likely need something stronger for complete relief. The smell can be off-putting to some pups and pawrents.

7. Zesty Paws Calming Dental Sticks

About: Zesty Paws Calming Dental Sticks are a fun twist on anti-anxiety treatment. Made with a soothing mix containing chamomile and valerian root, the manufacturer reports that they’re safe for use as-needed.

Best Calming Dental Chews

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Zesty Paws OraStix for Dogs - Calming Dental Sticks for Stress and Anxiety Relief with Hemp Melatonin Chamomile Dog Tartar Teeth Cleaning Calm Composure for Fireworks and Thunderstorms 25oz

Zesty Paws Calming Dental Sticks

These US-made calming treats are great for helping your dog relax, while also promoting dental health and fresh breath.


  • Promote relaxation without drowsiness
  • Peppermint flavor freshens breath
  • Chew design keeps your anxious pooch busy and cleans his teeth
  • Made in the USA using a grain-free formula

Options: Available in one flavor, one concentration, and two quantities: a 12-ounce and 25-ounce package.

Ingredients List

Chickpea, Tapioca Flour, Coconut Glycerin, Hemp Protein, Brewer’s Yeast...,

Bone Broth Powder, Chamomile, Valerian Root, Lactic Acid, Kelp Meal, Sorbic Acid, L-theanine, Magnesium Citrate, Taurine, Rosemary, Peppermint Oil, Citric Acid, Hemp Extract, Melatonin


This supplement contains a few different potentially effective supplements — including chamomile, valerian root, and L-theanine — that are widely thought to be safe. The innovative design keeps an anxious dog busy with a treat — combining an attention-grabbing activity with the soothing ingredients they need. The added dental hygiene boost is an added bonus. 


Since these are a chew design, they may not be best for daily use or quick relief. These can also be a choking hazard if your dog doesn’t chew them properly.

8. Rescue Remedy for Pets

About: Rescue Remedy Stress Relief Drops for Pets are plant-based and alcohol-free. Suitable for one time or ongoing calming applications, the manufacturer reports that the formula can be used on dogs, cats, lizards, and more.

Best Liquid Calming Product

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Bach RESCUE REMEDY PET Dropper 20mL, Natural Stress and Tension Relief, Calming for Dogs, Cats, and Other Pets, Homeopathic Flower Remedy, Thunder, Fireworks and Travel, Sedative-Free

Rescue Remedy Stress for Pets

This liquid calming supplement makes it easy to treat anxiety in dogs of all sizes and — unlike many similar products — doesn’t require refrigeration.


  • Flavorless, making it easy to mix into food or water
  • Made in England 
  • Doesn’t require refrigeration
  • Usable for dogs of all ages and sizes

Options: Available in one flavor, one concentration, and two quantities: 10-mL and 20-mL bottles with dropper included.

Ingredients List

HPUS 5x dilution of Helianthemum nummularium, Clematis vitalba, Impatiens glandulifera, Prunus cerasifera, Ornithogalum umbellatum...,


Designed to be fast-acting, some owners reported that the product brought relief within minutes rather than hours, which is ideal for thunderstorms, fireworks, and grooming. Great for picky dogs that dislike flavored supplements or allergy-prone dogs sensitive to additives.  


The ingredients aren’t as studied as others in terms of effectiveness, basic homeopathic principles lack scientific support, and high amounts of Ornithogalum umbellatum can be dangerous. Results are also mixed across the board with pooches.

9. STRELLALAB Hemp Calming Treats

About: STRELLALAB’s Hemp Calming Treats use hemp and other organic ingredients in an effort to soothe dogs suffering with anxiety. These can be used daily or for occasional treatment for storms or fireworks.  

Best Calming Chews for Dogs with Dental Issues

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STRELLALAB Hemp Calming Treats for Dogs - 120 Soft Chews - Made in USA with Hemp Oil - Dog Anxiety Relief - Natural Separation Aid - Stress Relief - Fireworks - Storms - Aggressive Behavior - Barking

STRELLALAB Hemp Calming Treats

Because they’re quite soft and easy to chew, these hemp-based calming treats work well for older dogs or those with oral health problems.


  • The soft chew form is teeth-friendly and crushes easily over food if needed
  • The 120-count container lasts between 24-120 days, depending on your dog’s weight
  • Made in the USA with no corn, soy, or dairy
  • Dosing starts for dogs over 25 pounds to those over 100 pounds

Options: Only available in one size, concentration, and flavor.

Ingredients List

Organic Hemp Seed Oil, Organic Hemp Protein Powder, Organic Chamomile Powder, Organic Passion Flower, Valerian Root...,

L-Tryptophan, Organic Ginger Root Powder


Since this product often yields results in as little as 30 minutes, it’s a good choice for easing anxiety surrounding storms or fireworks. Taste is also a highlight with pooches.


This is another product that contains hemp seed oil, which some owners may mistakenly suspect contains CBD. However, there is very little CBD present in the seeds of hemp plants. Some dogs may need a stronger supplement to see results. The sizing is a little large too, especially if your dog requires multiple treats for his weight.

10. Ready Pet Go! Natural Calming Treats

About: Ready Pet Go!’s Calming Treats come in 90-count packages, offering up to a 3-month supply depending on your dog’s weight. Made with hemp powder, chamomile, and more, these treats seek to give your pooch a touch of relaxation using natural ingredients.

Best Tasting Calming Chews

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Calming Treats for Dogs | Dog Anxiety Relief Calming Chews with Chamomile & Ginger | Supports Separation Anxiety, Sleep, Barking, Fireworks, Storms, Pet Anxiety, USA Made | 90 Calming Chews for Dogs

Ready Pet Go! Natural Calming Treats

Made at a GMP-certified, FDA-registered facility, these high-quality treats feature a bacon-and-cheese flavor that’s sure to tempt your pooch’s palate.


  • Come in a tasty bacon and cheese flavor
  • Safe for daily use to help ease ongoing anxiety or on an as-needed basis for fireworks and storms
  • Safe for puppies to adult doggos according to the manufacturer 
  • Made in the USA at a GMP-certified, FDA-registered facility

Options: Only available in one size, concentration, and flavor.

Ingredients List

Hemp Powder, Thiamine Mononitrate, Chamomile, Valerian Root, L-Theanine...,

Passion Flower, Ginger Root, L-Tryptophan, Magnesium Gluconate, Hemp Extract, Chickpea Flour, Potato Flour, Sunflower Lecithin, Cane Molasses, Purified Water, Tapioca Starch, Cheese Flavor, Safflower Oil, Glycerin, Bacon Flavor, Ascorbic Acid, Sorbic Acid, Mixed Tocopherols


The intended calming ingredients of hemp powder, chamomile, and valerian root are believed to be safe for puppers. Taste was also mostly a hit with pups — a tricky spot with many calming supplements.


While yummy, the included flavorings could be an issue for dogs with food sensitivities. Not every owner reported seeing a difference in their doggo’s behavior either.

dog needs calming treats

Different Types of Calming Supplements

As with all medications, calming supplements come in several forms for administering. Which form works best will vary by your dog’s preference and overall medication tolerance. The most common types are: 


Typically flavored with peanut butter or a protein as an incentive, chews are given to your dog like a treat.


Most dogs will eat a chew without a problem, but they can be crumbled over food if needed. They’re usually soft and easy to eat for doggos with missing or failing teeth and few require refrigeration.


The added flavors or proteins can be an issue with allergy-prone dogs. Not every dog is keen on the taste either, and they aren’t as easy to administer as tablets if he refuses to eat them.


This liquid-extract form is administered orally or over food via a dropper. 


Mixing a tincture into your dog’s food is effortless. It’s liquid, so it absorbs into kibble or wet food and mixes well. Some are flavorless, which is ideal for picky pupperonis.


Some dogs will turn their noses up to tincture-tainted food. Administering tincture orally can be messy. Many tinctures require refrigeration before or after use.


Tablet-form supplements are typically round pills that may or may not be flavored.


Tablets can easily be slipped into something else like cheese or pill pockets for administering. They’re also easy to force your dog to swallow if needed. Generally, they do not require refrigeration.


Picky doggos can be hard to trick into accepting a tablet, whether it’s flavored or not. For tablets containing artificial flavors, allergies can be a concern.

What Kinds of Dogs Can Benefit from Calming Supplements?

Like all treatments, calming supplements work better in some cases than others. Dogs who typically benefit from calming supplements are:

  • Dealing with separation anxiety: If your dog fears being alone, a calming supplement can give him the temporary relief he needs when you need to venture out without him.
  • Fearful of loud noises: Storms and fireworks aren’t an everyday event, making the occasional calming supplement ideal for controlling your dog’s anxiety as needed.
  • Suffering from generalized anxiety: Some pups are nervous Nellies by nature, and a calming supplement can provide everyday relief without a prescription.
  • Recently adopted: Joining a new family and routine is stressful. Relaxing your new friend with a calming supplement can smooth out the adjustment period.
Dog needs anxiety help

Additional Steps to Soothing Your Anxious Dog

While calming supplements can help your dog relax, the best approach to tackle anxiety is a comprehensive one.

Treating the source of your dog’s anxiety through counter-conditioning and training, rather than only masking the stress symptoms, is always ideal.

Dogs with more serious anxiety may need the help of more high-dose dog anxiety medication that can be more powerful than the supplements covered here. Talking with your vet can narrow down the best treatment plan. 

Other tools and techniques you can use include:

  • Increasing exercise: Upping your dog’s activity levels can alleviate stress. This is particularly important in woofers exhibiting anxiety related to a change in routine.
  • Crate training: An anxiety-proof crate gives your pooch a place to unwind, feel safe, and relax. Ideal for keeping dogs with separation anxiety safe and out of trouble, a crate can also be used to isolate your storm-fearing dog with calming music during thunder.
  • Thundershirt: Like swaddling a baby, a Thundershirt provides your dog with security when he’s feeling anxious during an event, like a storm or fireworks. Snug but not restrictive, thundershirts may be used alone or in combination with another anxiety-controlling method.
  • Prescribed medication: For doggos with severe anxiety, medication like Xanax may be the best option. These specially formulated medications target chemicals in your pupper’s brain to help him relax.
  • Desensitization/Counterconditioning: If specific things send your pup’s anxiety through the roof like other dogs, desensitization or counterconditioning training can tackle his fear. This gradual training exposes your pooch to his trigger over time, reducing and finally eliminating the phobia and subsequent anxiety. 
  • Providing a chew toy: Chewing and licking help to release endorphins in your doggo’s brain, which will help calm him down a bit. Plus, these types of anxiety dog toys and chews help keep his brain busy too.


Have you tried any of the calming supplements above or another with your pooch? What works best for calming your doggo? Let us know in the comments.

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Written by

Meg Marrs

Meg Marrs is the Founder and Director of Marketing at K9 of Mine. She is a lifelong canine enthusiast and adores dogs of all shapes and sizes! She loves iced coffee, hammocks, and puppy-cuddling!


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